Vortioxetine hydrobromide

Vortioxetine hydrobromide is a hydrobromide salt form of vortioxetine, a serotonin (5-HT) modulator and stimulator, with antidepressant activity. Vortioxetine inhibits the reuptake of serotonin and norepinephrine from the synaptic cleft and acts variably as a serotonin receptor agonist (5-HT1A), partial agonist (5-HT1B) or antagonist (5-HT3, 5-HT1D and 5-HT7). It is not clear how this agent’s purported multimodal mechanism of action contributes to its antidepressant effect; however, it is presumed to increase the synaptic availability of serotonin and norepinephrine. It is grouped under the following drug class(es): Neurotransmitter agents, Selective Serotonin Reuptake Inhibitors and Serotonin agents. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Trintellix and Brintellix. Its PubChem CID is 56843850.