Verteporfin

Verteporfin is a photosensitizing agent used in photodynamic therapy (PDT) to treat age-related macular degeneration (AMD), particularly the wet form with choroidal neovascularization. After intravenous administration, it localizes in abnormal blood vessels in the eye. When activated by non-thermal red light (689 nm), it produces reactive oxygen species (ROS) that selectively damage those vessels, reducing vision loss. Its therapeutic use is listed as ophthalmic agents. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Visudyne and Verteporfinum. Its PubChem SID is 483927867.