Vernakalant hydrochloride

Vernakalant hydrochloride is an intravenous anti-arrhythmic drug used for the rapid conversion of recent-onset atrial fibrillation (AF) or atrial flutter to a normal sinus rhythm, particularly effective for short-duration AF in patients with mild-to-moderate heart conditions or after cardiac surgery. It works by selectively affecting atrial ion channels, making it an atrial-specific agent that helps reset the heart’s rhythm quickly, often allowing for earlier hospital discharge, though its availability varies by region. Its therapeutic use is listed as antiarrhythmics. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Brinavess and Kynapid. Its PubChem CID is 9930048.

CAS No 748810-28-8
Molecular Formula C20H32ClNO4
Molecular Weight 385.9 g/mol
Synonyms (3R)-1-[(1R,2R)-2-[2-(3,4-dimethoxyphenyl)ethoxy]cyclohexyl]pyrrolidin-3-ol;hydrochloride

Frequently Asked Questions