Vernakalant hydrochloride is an intravenous anti-arrhythmic drug used for the rapid conversion of recent-onset atrial fibrillation (AF) or atrial flutter to a normal sinus rhythm, particularly effective for short-duration AF in patients with mild-to-moderate heart conditions or after cardiac surgery. It works by selectively affecting atrial ion channels, making it an atrial-specific agent that helps reset the heart’s rhythm quickly, often allowing for earlier hospital discharge, though its availability varies by region. Its therapeutic use is listed as antiarrhythmics. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Brinavess and Kynapid. Its PubChem CID is 9930048.
Vernakalant hydrochloride
| CAS No | 748810-28-8 |
|---|---|
| Molecular Formula | C20H32ClNO4 |
| Molecular Weight | 385.9 g/mol |
| Synonyms | (3R)-1-[(1R,2R)-2-[2-(3,4-dimethoxyphenyl)ethoxy]cyclohexyl]pyrrolidin-3-ol;hydrochloride |
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Vernakalant hydrochloride is an intravenous anti-arrhythmic drug used for the rapid conversion of recent-onset atrial fibrillation (AF) or atrial flutter to a normal sinus rhythm, particularly effective for short-duration AF in patients with mild-to-moderate heart conditions or after cardiac surgery.
The listed CAS number is 748810-28-8.
The listed molecular formula is C20H32ClNO4.
The listed molecular weight is 385.9 g/mol.
(3R)-1-[(1R,2R)-2-[2-(3,4-dimethoxyphenyl)ethoxy]cyclohexyl]pyrrolidin-3-ol;hydrochloride.
The source lists Brinavess and Kynapid.