Valdecoxib is a sulfonamide derivative and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities. Valdecoxib selectively binds to and inhibits cyclooxygenase (COX)-2, thereby preventing the conversion of arachidonic acid into prostaglandins, which are involved in the regulation of pain, inflammation, and fever. This NSAID does not inhibit COX-1 at therapeutic concentrations and therefore does not interfere with blood coagulation. It is grouped under the following drug class(es): Cyclooxygenase‑2 (COX‑2) Inhibitors and Non-Steroidal Anti-Inflammatory Drugs (NSAID). Its therapeutic use is listed as analgesics, anti-inflammatories and antipyretics. The directory classifies it as a discontinued API with a synthetic source/manufacturing origin. Other names for this substance include Bextra, Valdyn and valdecoxibum. Its PubChem CID is 119607.
Valdecoxib
| CAS No | 181695-72-7 |
|---|---|
| Molecular Formula | C16H14N2O3S |
| Molecular Weight | 314.4 g/mol |
| Synonyms | 4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzenesulfonamide |
Zoho Contact Form
"*" indicates required fields
Frequently Asked Questions
Valdecoxib is a sulfonamide derivative and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities.
The listed CAS number is 181695-72-7.
The listed molecular formula is C16H14N2O3S.
The listed molecular weight is 314.4 g/mol.
4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzenesulfonamide.
The source lists Bextra, Valdyn and valdecoxibum.