Trimethoprim Sulfate is the sulfate salt form of trimethoprim, a synthetic substituted pyrimidine with antibacterial activity. Trimethoprim sulfate selectively binds to and reversibly inhibits dihydrofolate reductase, thereby blocking the production of tetrahydrofolic acid from dihydrofolic acid. This leads to an inhibition of bacterial synthesis of folic acid, thereby affecting nucleic acid and protein synthesis. Trimethoprim sulfate has a stronger binding affinity for the bacterial enzyme than for the corresponding mammalian enzyme. Its therapeutic use is listed as antibacterials. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Trimethoprim sulphate. Its PubChem CID is 64936.
Trimethoprim sulfate
| CAS No | 56585-33-2 |
|---|---|
| Molecular Formula | C28H38N8O10S |
| Molecular Weight | 678.7 g/mol |
| Synonyms | sulfuric acid;5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine |
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Trimethoprim Sulfate is the sulfate salt form of trimethoprim, a synthetic substituted pyrimidine with antibacterial activity. Trimethoprim sulfate selectively binds to and reversibly inhibits dihydrofolate reductase, thereby blocking the production of tetrahydrofolic acid from dihydrofolic acid.
The listed CAS number is 56585-33-2.
The listed molecular formula is C28H38N8O10S.
The listed molecular weight is 678.7 g/mol.
sulfuric acid;5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine.
The source lists Trimethoprim sulphate.