Trimethoprim-Sulfamethoxazole is a synthetic combination of two antibacterial agents, trimethoprim and sulfamethoxazole. This synergistic combination, also known as Co-Trimoxazole, inhibits two sequential steps in the bacterial metabolism of folic acid. Trimethoprim is a pyrimidine inhibitor of dihydrofolate reductase; sulfamethoxazole is a sulfamide inhibitor of bacterial dihydrofolate synthase. Its therapeutic use is listed as antibiotics. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include sulfamethoxazole & trimethoprim, sulfamethoxazole + trimethoprim, Cotrimoxazol, Sulfotrimin, Supracombin and Bactromin. Its PubChem CID is 358641.
Trimethoprim-sulfamethoxazole
| CAS No | 8064-90-2 |
|---|---|
| Molecular Formula | C24H29N7O6S |
| Molecular Weight | 543.6 g/mol |
| Synonyms | 4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide;5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine |
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Frequently Asked Questions
Trimethoprim-Sulfamethoxazole is a synthetic combination of two antibacterial agents, trimethoprim and sulfamethoxazole. This synergistic combination, also known as Co-Trimoxazole, inhibits two sequential steps in the bacterial metabolism of folic acid.
The listed CAS number is 8064-90-2.
The listed molecular formula is C24H29N7O6S.
The listed molecular weight is 543.6 g/mol.
4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide;5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine.
The source lists sulfamethoxazole & trimethoprim, sulfamethoxazole + trimethoprim, Cotrimoxazol, Sulfotrimin, Supracombin and Bactromin.