Trifluridine is a fluorinated pyrimidine nucleoside that is structurally related to [idoxuridine]. It is an active antiviral agent in ophthalmic solutions used mainly in the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to herpes simplex virus. It displays effective antiviral activity against Herpes simplex virus type 1 and 2. It is grouped under the following drug class(es): DNA polymerase inhibitors and Nucleosides. Its therapeutic use is listed as antineoplastics and ophthalmic agents. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Trifluorothymidine, Viroptic, Trifluoromethyldeoxyuridine, Fluridine and Virophta. Its PubChem CID is 6256.
Trifluridine
| CAS No | 70-00-8 |
|---|---|
| Molecular Formula | C10H11F3N2O5 |
| Molecular Weight | 296.20 g/mol |
| Synonyms | 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(trifluoromethyl)pyrimidine-2,4-dione |
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Trifluridine is a fluorinated pyrimidine nucleoside that is structurally related to [idoxuridine]. It is an active antiviral agent in ophthalmic solutions used mainly in the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to herpes simplex virus.
The listed CAS number is 70-00-8.
The listed molecular formula is C10H11F3N2O5.
The listed molecular weight is 296.20 g/mol.
1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(trifluoromethyl)pyrimidine-2,4-dione.
The source lists Trifluorothymidine, Viroptic, Trifluoromethyldeoxyuridine, Fluridine and Virophta.