Tolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase (COMT). It is used to treat Parkinson’s disease as an adjunct to levodopa/carbidopa medication. It is a yellow, odorless, non-hygroscopic, crystalline compound. Tolcapone is associated with a risk of hepatotoxicity. Tolcapone is a Catechol-O-Methyltransferase Inhibitor. The mechanism of action of tolcapone is as a Catechol O-Methyltransferase Inhibitor. It is grouped under the following drug class(es): Dopamine agents and Neurotransmitter agents. Its therapeutic use is listed as antiparkinsonian agents and central nervous system (CNS) agents. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Tasmar, Tolcapona and Tolcaponum. Its PubChem CID is 4659569.
Tolcapone
| CAS No | 134308-13-7 |
|---|---|
| Molecular Formula | C14H11NO5 |
| Molecular Weight | 273.24 g/mol |
| Synonyms | (3,4-dihydroxy-5-nitrophenyl)-(4-methylphenyl)methanone |
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Frequently Asked Questions
Tolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase (COMT). It is used to treat Parkinson's disease as an adjunct to levodopa/carbidopa medication.
The listed CAS number is 134308-13-7.
The listed molecular formula is C14H11NO5.
The listed molecular weight is 273.24 g/mol.
(3,4-dihydroxy-5-nitrophenyl)-(4-methylphenyl)methanone.
The source lists Tasmar, Tolcapona and Tolcaponum.