Tiludronate Disodium is the disodium salt form of tiludronate, a first-generation, non-nitrogenous bisphosphonate analogue of endogenous pyrophosphate. Tiludronate adsorbs to hydroxyapatite cells, and although the exact mechanism through which this bisphosphonate exerts its effect has yet to be fully elucidated, tiludronate appears to inhibit protein-tyrosine-phosphatase (PTP) in osteoclasts, thereby disrupting the cytoskeletal ring structure and suppressing the bone resorbing activity of osteoclasts. It is grouped under the following drug class(es): Bisphosphonates. Its therapeutic use is listed as anti-osteoporosis agents. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Tildren, Skelid and Tiludronic Acid (disodium). Its PubChem CID is 60936.
Tiludronate disodium
| CAS No | 149845-07-8 |
|---|---|
| Molecular Formula | C7H7ClNa2O6P2S |
| Molecular Weight | 362.57 g/mol |
| Synonyms | disodium;[(4-chlorophenyl)sulfanyl-[hydroxy(oxido)phosphoryl]methyl]-hydroxyphosphinate |
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Frequently Asked Questions
Tiludronate Disodium is the disodium salt form of tiludronate, a first-generation, non-nitrogenous bisphosphonate analogue of endogenous pyrophosphate.
The listed CAS number is 149845-07-8.
The listed molecular formula is C7H7ClNa2O6P2S.
The listed molecular weight is 362.57 g/mol.
disodium;[(4-chlorophenyl)sulfanyl-[hydroxy(oxido)phosphoryl]methyl]-hydroxyphosphinate.
The source lists Tildren, Skelid and Tiludronic Acid (disodium).