Tigolaner

Tigolaner is an active ingredient in the feline parasitic treatment Felpreva® and is used to treat and prevent flea and tick infestations, as well as ear mite (Otodectes cynotis) and Notoedres (Notoedres cati) mange in cats. It is a topical spot-on treatment that provides up to 13 weeks of protection against fleas and ticks. Tigolaner works by blocking GABA-gated chloride channels in parasites, leading to their death. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include tigolanerum, Benzamide, 2-chloro-N-(1-cyanocyclopropyl)-5-(1′-methyl-3′-(1, 1, 2, 2, 2-pentafluoroethyl)-4′-(trifluoromethyl)(1 and 5′-bi-1H-pyrazol)-4-yl)-. Its PubChem CID is 77847513.

CAS No 1621436-41-6
Molecular Formula C21H13ClF8N6O
Molecular Weight 552.8 g/mol
Synonyms 2-chloro-N-(1-cyanocyclopropyl)-5-[1-[1-methyl-3-(1,1,2,2,2-pentafluoroethyl)-4-(trifluoromethyl)pyrazol-5-yl]pyrazol-4-yl]benzamide

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