Ticagrelor

Ticagrelor is a triazolopyrimidine that is an adenosine isostere; the cyclopentane ring is similar to ribose and the nitrogen-rich [1,2,3]triazolo[4,5-d]pyrimidine moiety resembles the nucleobase adenine. A platelet aggregation inhibitor that is used for prevention of thromboembolic events in patients with acute coronary syndrome. Among its listed roles, it functions as a platelet aggregation inhibitor and a P2Y12 receptor antagonist. It belongs to the class of triazolopyrimidines, an organofluorine compound, an aryl sulfide, a secondary amino compound and a hydroxyether. It is grouped under the following drug class(es): Antiplatelets and Antithrombotic agents. Its therapeutic use is listed as cardiovascular and hematologic agents. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Brilinta, Brilique and Possia. Its PubChem CID is 9871419.

CAS No 274693-27-5
Molecular Formula C23H28F2N6O4S
Molecular Weight 522.6 g/mol
Synonyms (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-propylsulfanyltriazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

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