Thiopental sodium is the sodium salt form of thiopental, an ultrashort-acting barbituric acid derivative, with anesthetic activity. Thiopental binds to the chloride ionophore site of the gamma-aminobutyric acid (GABA)-A/chloride ionophore receptor complex, thereby enhancing the inhibitory actions of GABA-A in the brain. This leads to synaptic inhibition, decreased neuronal excitability and induction of anesthesia. Additionally, this agent decreases glutamate (Glu) responses. It is grouped under the following drug class(es): Barbiturates and Sedatives. Its therapeutic use is listed as anesthetics. The directory classifies it as a discontinued API with a synthetic source/manufacturing origin. Other names for this substance include Pentothal, Leopental, Nesdonal and Ravonal. It is listed as a controlled drug substance (Schedule III). Its PubChem CID is 23665410.
Thiopental sodium
| CAS No | 71-73-8 |
|---|---|
| Molecular Formula | C11H17N2NaO2S |
| Molecular Weight | 264.32 g/mol |
| Synonyms | sodium;5-ethyl-4,6-dioxo-5-pentan-2-yl-1H-pyrimidine-2-thiolate |
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Frequently Asked Questions
Thiopental sodium is the sodium salt form of thiopental, an ultrashort-acting barbituric acid derivative, with anesthetic activity.
The listed CAS number is 71-73-8.
The listed molecular formula is C11H17N2NaO2S.
The listed molecular weight is 264.32 g/mol.
sodium;5-ethyl-4,6-dioxo-5-pentan-2-yl-1H-pyrimidine-2-thiolate.
The source lists Pentothal, Leopental, Nesdonal and Ravonal.