It is a versatile synthon used to construct complex bioactive molecules due to its stereochemically precise structure, featuring a protected piperidine ring with a chiral hydroxyl group. tert-Butyl (3S)-3-hydroxypiperidine-1-carboxylate is used mainly as a chiral building block in pharmaceutical synthesis, most notably as a key intermediate for ibrutinib, a B-cell malignancy drug.
tert-butyl (3S)-3-hydroxypiperidine-1-carboxylate
| API Name | Ibrutinib |
|---|---|
| CAS No | 143900-44-1 |
| Molecular Formula | C10H19NO3 |
| Molecular Weight | 201.26 g/mol |
| Synonyms | tert-butyl (3S)-3-hydroxypiperidine-1-carboxylate |
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