tert-butyl (3S)-3-hydroxypiperidine-1-carboxylate

It is a versatile synthon used to construct complex bioactive molecules due to its stereochemically precise structure, featuring a protected piperidine ring with a chiral hydroxyl group. tert-Butyl (3S)-3-hydroxypiperidine-1-carboxylate is used mainly as a chiral building block in pharmaceutical synthesis, most notably as a key intermediate for ibrutinib, a B-cell malignancy drug.

API Name Ibrutinib
CAS No 143900-44-1
Molecular Formula C10H19NO3
Molecular Weight 201.26 g/mol
Synonyms tert-butyl (3S)-3-hydroxypiperidine-1-carboxylate