Temsavir is the active form of the HIV drug fostemsavir (Rukobia), used in combination therapy for heavily treatment-experienced adults with multidrug-resistant HIV-1, working as a first-in-class attachment inhibitor by binding to the viral gp120 protein to block HIV from entering host CD4+ cells, thus preventing infection and offering benefits beyond just viral entry inhibition, like reducing immune activation. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Temsavirum, Piperazine, 1-benzoyl-4-((4-methoxy-7-(3-methyl-1H-1, 2, 4-triazol-1-yl)-1H-pyrrolo(2 and 3-C)pyridin-3-yl)oxoacetyl)-. Its PubChem CID is 11317439.
Temsavir
| CAS No | 701213-36-7 |
|---|---|
| Molecular Formula | C24H23N7O4 |
| Molecular Weight | 473.5 g/mol |
| Synonyms | 1-(4-benzoylpiperazin-1-yl)-2-[4-methoxy-7-(3-methyl-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]ethane-1,2-dione |
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Temsavir is the active form of the HIV drug fostemsavir (Rukobia), used in combination therapy for heavily treatment-experienced adults with multidrug-resistant HIV-1, working as a first-in-class attachment inhibitor by binding to the viral gp120 protein to block HIV from entering host CD4+ cells, thus preventing infection and offering benefits beyond just viral entry inhibition, like reducing immune activation.
The listed CAS number is 701213-36-7.
The listed molecular formula is C24H23N7O4.
The listed molecular weight is 473.5 g/mol.
1-(4-benzoylpiperazin-1-yl)-2-[4-methoxy-7-(3-methyl-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]ethane-1,2-dione.
The source lists Temsavirum, Piperazine, 1-benzoyl-4-((4-methoxy-7-(3-methyl-1H-1, 2, 4-triazol-1-yl)-1H-pyrrolo(2 and 3-C)pyridin-3-yl)oxoacetyl)-.