Telbivudine

Telbivudine is a pyrimidine 2′-deoxyribonucleoside that is the L-enantiomer of thymine. A synthetic thymidine nucleoside analogue with activity against HBV DNA polymerase. Among its listed roles, it functions as a antiviral drug and an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor. Functionally, it is related to thymine. It is an enantiomer of a thymidine. Telbivudine is a synthetic thymidine nucleoside analog with specific activity against the hepatitis B virus. Telbivudine is orally administered, with good tolerance, lack of toxicity and no dose-limiting side effects. It is grouped under the following drug class(es): DNA polymerase inhibitors, Nucleosides and Reverse Transcriptase Inhibitors. Its therapeutic use is listed as anti-infectives and antivirals. The directory classifies it as a discontinued API with a synthetic source/manufacturing origin. Other names for this substance include Epavudine, Tyzeka, Sebivo and L-Thymidine. Its PubChem CID is 159269.