Streptomycin

Streptomycin, an antibiotic derived from Streptomyces griseus, was the first aminoglycoside to be discovered and used in practice in the 1940s. Selman Waksman and eventually Albert Schatz were recognized with the Nobel Prize in Medicine for their discovery of streptomycin and its antibacterial activity. Although streptomycin was the first antibiotic determined to be effective against mycobacterium tuberculosis, it has fallen out of favor due to resistance and is now mainly used as adjunctive treatment in cases of multi-drug resistant tuberculosis. It is grouped under the following drug class(es): Aminoglycosides. Its therapeutic use is listed as anti-infectives, antibacterials, antibiotics and antituberculars. The directory classifies it as a commercial API with a fermentation-derived source/manufacturing origin. Other names for this substance include Strepcen, Gerox, Streptomycine, Estreptomicina, Agrimycin and Agrept. Its PubChem CID is 19649.

CAS No 57-92-1
Molecular Formula C21H39N7O12
Molecular Weight 581.6 g/mol
Synonyms 2-[(1R,2R,3S,4R,5R,6S)-3-(diaminomethylideneamino)-4-[(2R,3R,4R,5S)-3-[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy-2,5,6-trihydroxycyclohexyl]guanidine

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