Stavudine

Stavudine is a nucleoside analogue obtained by formal dehydration across positions 2 and 3 of thymidine. An inhibitor of HIV-1 reverse transcriptase Among its listed roles, it functions as a antimetabolite, an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor and an antiviral agent. It is an organic molecular entity, a nucleoside analogue and a dihydrofuran. Functionally, it is related to thymine. It is grouped under the following drug class(es): Dideoxynucleosides, DNA polymerase inhibitors, Nucleosides and Reverse Transcriptase Inhibitors. Its therapeutic use is listed as anti-infectives and antivirals. The directory classifies it as a discontinued API with a synthetic source/manufacturing origin. Other names for this substance include sanilvudine, Zerit, 2′ and 3′-Didehydro-3′-deoxythymidine. Its PubChem CID is 18283.