Somatrem is a recombinant analogue of human growth hormone (GH). Formerly marketed as Protropin, it was mainly prescribed to treat pediatric growth failure due to inadequate endogenous GH secretion. Somatrem has largely been superseded by somatropin, which features an identical molecular structure to the native hormone. It is grouped under the following drug class(es): Hormones. The directory classifies it as a discontinued API with a biotechnology source/manufacturing origin. Other names for this substance include Protropin, growth hormone and human methionyl. Its PubChem CID is 5487805.
Somatrem
| CAS No | 88389-69-9 |
|---|---|
| Molecular Formula | C43H72N14O14 |
| Molecular Weight | 1009.1 g/mol |
| Synonyms | (4S)-5-[[(2S)-1-[(2S)-2-[[2-[(2S)-2-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]carbamoyl]pyrrolidin-1-yl]-4-carboxy-1-oxobutan-2-yl]amino]-4-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-methylbutanoyl]amino]propanoyl]amino]-3-methylbutanoyl]amino]acetyl]amino]-5-oxopentanoic acid |
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Somatrem is a recombinant analogue of human growth hormone (GH). Formerly marketed as Protropin, it was mainly prescribed to treat pediatric growth failure due to inadequate endogenous GH secretion.
The listed CAS number is 88389-69-9.
The listed molecular formula is C43H72N14O14.
The listed molecular weight is 1009.1 g/mol.
(4S)-5-[[(2S)-1-[(2S)-2-[[2-[(2S)-2-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]carbamoyl]pyrrolidin-1-yl]-4-carboxy-1-oxobutan-2-yl]amino]-4-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-methylbutanoyl]amino]propanoyl]amino]-3-methylbutanoyl]amino]acetyl]amino]-5-oxopentanoic acid.
The source lists Protropin, growth hormone and human methionyl.