Methotrexate Sodium is the sodium salt of methotrexate, an antimetabolite with antineoplastic and immunomodulating properties. Methotrexate binds to and inhibits the enzyme dihydrofolate reductase, resulting in inhibition of purine nucleotide and thymidylate synthesis and, subsequently, inhibition of DNA and RNA syntheses. Methotrexate also exhibits potent immunosuppressant properties. Its therapeutic use is listed as anti-psoriatic agents, antineoplastics and antirheumatic agents. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Abitrexate, Trexall, Folex Pfs and Mexate. Its PubChem CID is 11329481.
Sodium methotrexate
| CAS No | 7413-34-5 |
|---|---|
| Molecular Formula | C20H20N8Na2O5 |
| Molecular Weight | 498.4 g/mol |
| Synonyms | disodium;(2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioate |
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Methotrexate Sodium is the sodium salt of methotrexate, an antimetabolite with antineoplastic and immunomodulating properties.
The listed CAS number is 7413-34-5.
The listed molecular formula is C20H20N8Na2O5.
The listed molecular weight is 498.4 g/mol.
disodium;(2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioate.
The source lists Abitrexate, Trexall, Folex Pfs and Mexate.