Sodium 17alpha-dihydroequilin sulfate

Sodium 17alpha-dihydroequilin sulfate (DHES) is a natural estrogen found in Premarin, used in hormonal therapies like hormone replacement (HRT) to manage menopause symptoms, potentially reducing bone loss and cardiovascular risk, but also studied for its specific effects on lipids and insulin. It’s a key component in conjugated equine estrogens (CEEs), acting as a natural estrogen with potential benefits like antioxidant properties, though its role and synergistic effects with other estrogens (like equilin) are still studied for comprehensive cardiovascular health. The directory classifies it as a commercial API with a natural source/manufacturing origin. Other names for this substance include 17alpha-Dihydroequilin sodium 3-sulfate and 17alpha-Dihydro Equilin 3-Sulfate Sodium Salt. It is also listed for alternate use as: API Intermediate. Its PubChem CID is 23671797.

CAS No 56050-05-6
Molecular Formula C18H21NaO5S
Molecular Weight 372.4 g/mol
Synonyms sodium [(9S,13S,14S,17R)-17-hydroxy-13-methyl-6,9,11,12,14,15,16,17-octahydrocyclopenta[a]phenanthren-3-yl] sulfate

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