Sivelestat sodium hydrate is used as a neutrophil elastase inhibitor, mainly for the treatment of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS), especially when associated with systemic inflammatory response syndrome (SIRS). It works by inhibiting neutrophil elastase, an enzyme released during inflammation that can damage lung tissue. By blocking this enzyme, sivelestat helps reduce inflammation and lung injury, improving respiratory function in critically ill patients. It is most commonly used in hospital settings, particularly in Japan and some other countries. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Sivelestat sodium salt tetrahydrate and LY544349 Sodium Hydrate. Its PubChem CID is 23663985.
Sivelestat sodium
| CAS No | 201677-61-4 |
|---|---|
| Molecular Formula | C20H29N2NaO11S |
| Molecular Weight | 528.5 g/mol |
| Synonyms | sodium;2-[[2-[[4-(2,2-dimethylpropanoyloxy)phenyl]sulfonylamino]benzoyl]amino]acetate;tetrahydrate |
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Frequently Asked Questions
Sivelestat sodium hydrate is used as a neutrophil elastase inhibitor, mainly for the treatment of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS), especially when associated with systemic inflammatory response syndrome (SIRS).
The listed CAS number is 201677-61-4.
The listed molecular formula is C20H29N2NaO11S.
The listed molecular weight is 528.5 g/mol.
sodium;2-[[2-[[4-(2,2-dimethylpropanoyloxy)phenyl]sulfonylamino]benzoyl]amino]acetate;tetrahydrate.
The source lists Sivelestat sodium salt tetrahydrate and LY544349 Sodium Hydrate.