Sirolimus

Sirolimus is a macrolide lactam isolated from Streptomyces hygroscopicus consisting of a 29-membered ring containing 4 trans double bonds, three of which are conjugated. It is an antibiotic, immunosupressive and antineoplastic agent. Among its listed roles, it functions as a immunosuppressive agent, an antineoplastic agent, an antibacterial drug, a mTOR inhibitor, a bacterial metabolite, an anticoronaviral agent and a geroprotector. It is a cyclic acetal, a cyclic ketone, an ether, a secondary alcohol, an organic heterotricyclic compound, an antibiotic antifungal drug and a macrolide lactam. It is grouped under the following drug class(es): Immunosuppressants and Kinase inhibitors. Its therapeutic use is listed as antineoplastics. The directory classifies it as a commercial API with a natural source/manufacturing origin. Other names for this substance include rapamycin, Rapamune, Perceiva and Cypher. Its PubChem CID is 5284616.