Simethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas bubbles to facilitate their elimination. It has a favourable safety profile as it is not systemically absorbed. Simethicone has been in use since the 1940s but was granted FDA approval in 1952. Simethicone is a mixture of polydimethylsiloxanes with antifoaming and anti-bloating effects. Simethicone reduces the surface tension of gas bubbles causing them to coalesce into larger bubbles that can be passed more easily by belching or flatulence. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Sentry Simethicone, Mylanta Gas Relief, Gas-X and Infacol. Its PubChem CID is 6433516.
Simethicone
| CAS No | 8050-81-5 |
|---|---|
| Molecular Formula | C6H18O4Si3 |
| Molecular Weight | 238.46 g/mol |
| Synonyms | dioxosilane;methoxy-dimethyl-trimethylsilyloxysilane |
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Frequently Asked Questions
Simethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas bubbles to facilitate their elimination. It has a favourable safety profile as it is not systemically absorbed.
The listed CAS number is 8050-81-5.
The listed molecular formula is C6H18O4Si3.
The listed molecular weight is 238.46 g/mol.
dioxosilane;methoxy-dimethyl-trimethylsilyloxysilane.
The source lists Sentry Simethicone, Mylanta Gas Relief, Gas-X and Infacol.