Setmelanotide acetate, sold under the brand name Imcivree, is a medication used to treat obesity in individuals with certain genetic conditions, including Bardet-Biedl syndrome (BBS) and deficiencies in POMC, PCSK1, or LEPR. It works by acting on the melanocortin-4 receptor (MC4R) in the brain, helping to reduce appetite and promote weight loss. It is grouped under the following drug class(es): MC4 receptor agonists and Peptides. Its therapeutic use is listed as weight loss agents. The directory classifies it as a commercial API with a peptide source/manufacturing origin. Other names for this substance include RM-493 acetate, Imcivree and Setmelanotide acetate?. Its PubChem CID is 155491122.
Setmelanotide acetate
| CAS No | 1504602-49-6 |
|---|---|
| Molecular Formula | C55H80N18O15S2 |
| Molecular Weight | 1297.5 g/mol |
| Synonyms | (4R,7S,10S,13R,16S,19R,22R)-22-[[(2S)-2-acetamido-5-(diaminomethylideneamino)pentanoyl]amino]-13-benzyl-10-[3-(diaminomethylideneamino)propyl]-16-(1H-imidazol-5-ylmethyl)-7-(1H-indol-3-ylmethyl)-19-methyl-6,9,12,15,18,21-hexaoxo-1,2-dithia-5,8,11,14,17,20-hexazacyclotricosane-4-carboxamide;acetic acid |
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Frequently Asked Questions
Setmelanotide acetate, sold under the brand name Imcivree, is a medication used to treat obesity in individuals with certain genetic conditions, including Bardet-Biedl syndrome (BBS) and deficiencies in POMC, PCSK1, or LEPR.
The listed CAS number is 1504602-49-6.
The listed molecular formula is C55H80N18O15S2.
The listed molecular weight is 1297.5 g/mol.
(4R,7S,10S,13R,16S,19R,22R)-22-[[(2S)-2-acetamido-5-(diaminomethylideneamino)pentanoyl]amino]-13-benzyl-10-[3-(diaminomethylideneamino)propyl]-16-(1H-imidazol-5-ylmethyl)-7-(1H-indol-3-ylmethyl)-19-methyl-6,9,12,15,18,21-hexaoxo-1,2-dithia-5,8,11,14,17,20-hexazacyclotricosane-4-carboxamide;acetic acid.
The source lists RM-493 acetate, Imcivree and Setmelanotide acetate?.