During the manufacturing process, the reaction initially forms a mixture of stereoisomers, including the trans-(±) form. This intermediate undergoes stereochemical conversion or resolution to obtain the desired cis-(1S,4S) sertraline hydrochloride, which is the pharmacologically active form used as the final API. Thus, trans-(±)-Sertraline Hydrochloride serves as an important precursor that is further processed to produce the active sertraline drug substance. Sertraline Hydrochloride trans-(±) serves as a key intermediate in the synthesis of sertraline.
Sertraline Hydrochloride, trans-(A+-)
| API Name | Sertraline |
|---|---|
| CAS No | 79620-28-3 |
| Molecular Formula | C17H18Cl3N |
| Molecular Weight | 342.7 g/mol |
| Synonyms | (1R,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine;hydrochloride |
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Frequently Asked Questions
During the manufacturing process, the reaction initially forms a mixture of stereoisomers, including the trans-(±) form. This intermediate undergoes stereochemical conversion or resolution to obtain the desired cis-(1S,4S) sertraline hydrochloride, which is the pharmacologically active form used as the final API. Thus, trans-(±)-Sertraline Hydrochloride serves as an important precursor that is further processed to produce the active sertraline drug substance. Sertraline Hydrochloride trans-(±) serves as a key intermediate in the synthesis of sertraline.
The CAS number of Sertraline Hydrochloride, trans-(A+-) is 79620-28-3.
The molecular formula of Sertraline Hydrochloride, trans-(A+-) is C17H18Cl3N.
The listed molecular weight of Sertraline Hydrochloride, trans-(A+-) is 342.7 g/mol.
Sertraline Hydrochloride, trans-(A+-) is listed as being used in connection with the following API: Sertraline.
The listed synonym or IUPAC name for Sertraline Hydrochloride, trans-(A+-) is (1R,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine;hydrochloride.