Salsalate is a dimeric benzoate ester obtained by intermolecular condensation between the carboxy of one molecule of salicylic acid with the phenol group of a second. It is a prodrug for salycylic acid that is used for treatment of rheumatoid arthritis and osteoarthritis and also shows activity against type II diabetes. Among its listed roles, it functions as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic, an antirheumatic drug, a hypoglycemic agent, an antineoplastic agent, an EC 3.5.2.6 (beta-lactamase) inhibitor and a prodrug. It is a benzoate ester, a member of benzoic acids, a member of phenols and a member of salicylates. Functionally, it is related to salicylic acid. It is grouped under the following drug class(es): Non-Steroidal Anti-Inflammatory Drugs (NSAID). Its therapeutic use is listed as analgesics, anti-inflammatories, antipyretics and osteoarthritis agents. The directory classifies it as a commercial API with a semi-synthetic source/manufacturing origin. Other names for this substance include sasapyrine, Salicylsalicylic acid and Disalicylic acid. Its PubChem CID is 5161.
Salsalate
| CAS No | 552-94-3 |
|---|---|
| Molecular Formula | C14H10O5 |
| Molecular Weight | 258.23 g/mol |
| Synonyms | 2-(2-hydroxybenzoyl)oxybenzoic acid |
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Frequently Asked Questions
Salsalate is a dimeric benzoate ester obtained by intermolecular condensation between the carboxy of one molecule of salicylic acid with the phenol group of a second.
The listed CAS number is 552-94-3.
The listed molecular formula is C14H10O5.
The listed molecular weight is 258.23 g/mol.
2-(2-hydroxybenzoyl)oxybenzoic acid.
The source lists sasapyrine, Salicylsalicylic acid and Disalicylic acid.