It provides the stereochemically pure (S)-oxetan-2-ylmethyl substituent required for the benzimidazole core of the drug molecule. (S)-oxetan-2-ylmethanamine 4-methylbenzenesulfonate is a critical key intermediate employed to synthesize Danuglipron (PF-06882961), an orally active, small-molecule GLP-1 receptor agonist.
(S)-oxetan-2-ylmethanamine 4-methylbenzenesulfonate
| API Name | Danuglipron |
|---|---|
| CAS No | 2740593-38-6 |
| Molecular Formula | C11H17NO4S |
| Molecular Weight | 259.32 g/mol |
| Synonyms | 4-methylbenzenesulfonic acid;[(2S)-oxetan-2-yl]methanamine |
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