After coupling, the protecting groups are removed in downstream processing. (S)-1-tert-Butyl 5-(2,5-dioxopyrrolidin-1-yl) 2-(18-(tert-butoxy)-18-oxooctadecanamido)pentanedioate is a protected fatty-acid linker intermediate used in peptide API synthesis.The molecule contains an activated N-hydroxysuccinimide (NHS) ester, enabling efficient acylation of peptide amino groups, while tert-butyl protecting groups provide stability and selectivity during multistep synthesis.
(S)-1-tert-Butyl 5-(2,5-dioxopyrrolidin-1-yl) 2-(18-(tert-butoxy)-18-oxooctadecanamido)pentanedioate
| API Name | Insulin degludec |
|---|---|
| CAS No | 1188328-22-4 |
| Molecular Formula | C35H60N2O9 |
| Molecular Weight | 652.9 g/mol |
| Synonyms | 1-O-tert-butyl 5-O-(2,5-dioxopyrrolidin-1-yl) (2S)-2-[[18-[(2-methylpropan-2-yl)oxy]-18-oxooctadecanoyl]amino]pentanedioate |
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Frequently Asked Questions
After coupling, the protecting groups are removed in downstream processing. (S)-1-tert-Butyl 5-(2,5-dioxopyrrolidin-1-yl) 2-(18-(tert-butoxy)-18-oxooctadecanamido)pentanedioate is a protected fatty-acid linker intermediate used in peptide API synthesis.The molecule contains an activated N-hydroxysuccinimide (NHS) ester, enabling efficient acylation of peptide amino groups, while tert-butyl protecting groups provide stability and selectivity during multistep synthesis.
The CAS number of (S)-1-tert-Butyl 5-(2,5-dioxopyrrolidin-1-yl) 2-(18-(tert-butoxy)-18-oxooctadecanamido)pentanedioate is 1188328-22-4.
The molecular formula of (S)-1-tert-Butyl 5-(2,5-dioxopyrrolidin-1-yl) 2-(18-(tert-butoxy)-18-oxooctadecanamido)pentanedioate is C35H60N2O9.
The listed molecular weight of (S)-1-tert-Butyl 5-(2,5-dioxopyrrolidin-1-yl) 2-(18-(tert-butoxy)-18-oxooctadecanamido)pentanedioate is 652.9 g/mol.
(S)-1-tert-Butyl 5-(2,5-dioxopyrrolidin-1-yl) 2-(18-(tert-butoxy)-18-oxooctadecanamido)pentanedioate is listed as being used in connection with the following API: Insulin degludec.
The listed synonym or IUPAC name for (S)-1-tert-Butyl 5-(2,5-dioxopyrrolidin-1-yl) 2-(18-(tert-butoxy)-18-oxooctadecanamido)pentanedioate is 1-O-tert-butyl 5-O-(2,5-dioxopyrrolidin-1-yl) (2S)-2-[[18-[(2-methylpropan-2-yl)oxy]-18-oxooctadecanoyl]amino]pentanedioate.