The molecule includes a tert-butoxycarbonyl (Boc) protecting group, which masks the piperidine nitrogen during multi-step synthesis. It is a complex drug-like intermediate often used in medicinal chemistry, especially in the development of kinase inhibitors and other targeted therapeutics. The rigid heterocyclic system and aromatic groups contribute to strong binding interactions in biological targets. (R)-tert-Butyl 3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate is a chiral, Boc-protected piperidine derivative containing a fused pyrazolo[3,4-d]pyrimidine heterocyclic core linked to a 4-phenoxyphenyl substituent.
(R)-tert-Butyl 3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate
| API Name | Ibrutinib |
|---|---|
| CAS No | 1022150-11-3 |
| Molecular Formula | C27H30N6O3 |
| Molecular Weight | 486.6 g/mol |
| Synonyms | tert-butyl (3R)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate |
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Frequently Asked Questions
The molecule includes a tert-butoxycarbonyl (Boc) protecting group, which masks the piperidine nitrogen during multi-step synthesis. It is a complex drug-like intermediate often used in medicinal chemistry, especially in the development of kinase inhibitors and other targeted therapeutics. The rigid heterocyclic system and aromatic groups contribute to strong binding interactions in biological targets. (R)-tert-Butyl 3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate is a chiral, Boc-protected piperidine derivative containing a fused pyrazolo[3,4-d]pyrimidine heterocyclic core linked to a 4-phenoxyphenyl substituent.
The CAS number of (R)-tert-Butyl 3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate is 1022150-11-3.
The molecular formula of (R)-tert-Butyl 3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate is C27H30N6O3.
The listed molecular weight of (R)-tert-Butyl 3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate is 486.6 g/mol.
(R)-tert-Butyl 3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate is listed as being used in connection with the following API: Ibrutinib.
The listed synonym or IUPAC name for (R)-tert-Butyl 3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate is tert-butyl (3R)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate.