This intermediate is coupled with a western fragment and converted to the salt in the final stage. (R)-Ozanimod, typically defined as an intermediate leading to the S-enantiomer of Ozanimod, is employed to synthesize Ozanimod hydrochloride by establishing the crucial chiral amine center, often through chiral ruthenium-catalyzed reduction of an imine intermediate or enzymatic resolution.
(R)-Ozanimod
| API Name | Ozanimod hydrochloride |
|---|---|
| CAS No | 1306760-85-9 |
| Molecular Formula | C23H25ClN4O3 |
| Molecular Weight | 440.9 g/mol |
| Synonyms | 5-[3-[(1R)-1-(2-hydroxyethylamino)-2,3-dihydro-1H-inden-4-yl]-1,2,4-oxadiazol-5-yl]-2-propan-2-yloxybenzonitrile;hydrochloride |
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