Quinine sulfate

Quinine Sulfate is the sulfate salt form of the quinidine alkaloid isolate quinine. Quinine has many mechanisms of action, including reduction of oxygen intake and carbohydrate metabolism; disruption of DNA replication and transcription via DNA intercalation; and reduction of the excitability of muscle fibers via alteration of calcium distribution. This agent also inhibits the drug efflux pump P-glycoprotein that is overexpressed in multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents. (NCI04). Its therapeutic use is listed as antimalarials. The directory classifies it as a commercial API with a natural source/manufacturing origin. Other names for this substance include Qualaquin and Coco-Quinine. Its PubChem CID is 16051948.

CAS No 804-63-7
Molecular Formula C40H50N4O8S
Molecular Weight 746.9 g/mol
Synonyms (R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol;sulfuric acid

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