Quinidine polygalacturonate is an oral salt form of the antiarrhythmic drug quinidine, historically marketed in the U.S. under the brand name Cardioquin for treatment and prevention of certain supraventricular and ventricular arrhythmias. It is a class Ia antiarrhythmic that works by blocking cardiac sodium and potassium channels, thereby prolonging the action potential and QT interval, but its use has markedly declined due to proarrhythmic risk and availability issues. Its therapeutic use is listed as antiarrhythmics and cardiovascular. The directory classifies it as a discontinued API with a semi-synthetic source/manufacturing origin. Other names for this substance include Cardioquin, Galactoquin and Naticardina. Its PubChem CID is 18469864.
Quinidine polygalacturonate
| CAS No | 27555-34-6 |
|---|---|
| Molecular Formula | C26H34N2O9 |
| Molecular Weight | 518.6 g/mol |
| Synonyms | (5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl)-(6-methoxyquinolin-4-yl)methanol;2,3,4,5-tetrahydroxy-6-oxohexanoic acid |
Zoho Contact Form
"*" indicates required fields
Frequently Asked Questions
S. under the brand name Cardioquin for treatment and prevention of certain supraventricular and ventricular arrhythmias.
The listed CAS number is 27555-34-6.
The listed molecular formula is C26H34N2O9.
The listed molecular weight is 518.6 g/mol.
(5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl)-(6-methoxyquinolin-4-yl)methanol;2,3,4,5-tetrahydroxy-6-oxohexanoic acid.
The source lists Cardioquin, Galactoquin and Naticardina.