Quinidine gluconate

Quinidine Gluconate is the gluconate salt form of quinidine, an alkaloid with antimalarial and antiarrhythmic (Class la) properties. Quinidine gluconate exerts its anti-malarial activity by acting mainly as an intra-erythrocytic schizonticide through association with the hemepolymer (hemozoin) in the acidic food vacuole of the parasite thereby preventing further polymerization by heme polymerase enzyme. Its therapeutic use is listed as antiarrhythmics and cardiovascular. The directory classifies it as a commercial API with a semi-synthetic source/manufacturing origin. Other names for this substance include Duraquin and Quinaglute. Its PubChem CID is 94328.

CAS No 7054-25-3
Molecular Formula C26H36N2O9
Molecular Weight 520.6 g/mol
Synonyms (S)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol;(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoic acid

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