Proguanil is a biguanide compound which has isopropyl and p-chlorophenyl substituents on the terminal N atoms. A prophylactic antimalarial drug, it works by inhibiting the enzyme dihydrofolate reductase, that is involved in the reproduction of the malaria parasites Plasmodium falciparum and P. It is grouped under the following drug class(es): Biguanides. Its therapeutic use is listed as anti-infectives, antimalarials and antiparasitics. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Chlorguanid and Bigumal. Its PubChem CID is 6178111.
Proguanil
| CAS No | 500-92-5 |
|---|---|
| Molecular Formula | C11H16ClN5 |
| Molecular Weight | 253.73 g/mol |
| Synonyms | (1E)-1-[amino-(4-chloroanilino)methylidene]-2-propan-2-ylguanidine |
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Frequently Asked Questions
Proguanil is a biguanide compound which has isopropyl and p-chlorophenyl substituents on the terminal N atoms. A prophylactic antimalarial drug, it works by inhibiting the enzyme dihydrofolate reductase, that is involved in the reproduction of the malaria parasites Plasmodium falciparum and P.
The listed CAS number is 500-92-5.
The listed molecular formula is C11H16ClN5.
The listed molecular weight is 253.73 g/mol.
(1E)-1-[amino-(4-chloroanilino)methylidene]-2-propan-2-ylguanidine.
The source lists Chlorguanid and Bigumal.