Piroxicam

Piroxicam is a monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid 1,1-dioxide with the exocyclic nitrogen of 2-aminopyridine. A non-steroidal anti-inflammatory drug of the oxicam class, it is used to relieve pain and works by preventing the production of endogenous prostaglandins involved in the mediation of pain, stiffness, tenderness and swelling. Among its listed roles, it functions as a analgesic, a cyclooxygenase 1 inhibitor, a non-steroidal anti-inflammatory drug, an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor and an antirheumatic drug. It is a benzothiazine, a member of pyridines and a monocarboxylic acid amide. It is grouped under the following drug class(es): Cyclooxygenase‑1 (COX‑1) Inhibitors and Non-Steroidal Anti-Inflammatory Drugs (NSAID). Its therapeutic use is listed as analgesics, anti-inflammatories, antipyretics, ophthalmic agents and osteoarthritis agents. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Feldene and Piroxicamum. Its PubChem CID is 54676228.

CAS No 36322-90-4
Molecular Formula C15H13N3O4S
Molecular Weight 331.3 g/mol
Synonyms 4-hydroxy-2-methyl-1,1-dioxo-N-pyridin-2-yl-1λ6,2-benzothiazine-3-carboxamide

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