It is often converted to phenylhydrazine in situ using bases like sodium hydroxide or sodium dithionite, achieving high yields (>85%) and purity. Phenylhydrazine hydrochloride is a key, cost-effective starting material in the synthesis of Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), typically reacting with ethyl acetoacetate via condensation and cyclization.
Phenylhydrazine hydrochloride
| API Name | Edaravone |
|---|---|
| CAS No | 59-88-1 |
| Molecular Formula | C6H8N2.ClH |
| Molecular Weight | 144.60 g/mol |
| Synonyms | phenylhydrazine;hydrochloride |
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Frequently Asked Questions
It is often converted to phenylhydrazine in situ using bases like sodium hydroxide or sodium dithionite, achieving high yields (>85%) and purity. Phenylhydrazine hydrochloride is a key, cost-effective starting material in the synthesis of Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), typically reacting with ethyl acetoacetate via condensation and cyclization.
The CAS number of Phenylhydrazine hydrochloride is 59-88-1.
The molecular formula of Phenylhydrazine hydrochloride is C6H8N2.ClH.
The listed molecular weight of Phenylhydrazine hydrochloride is 144.60 g/mol.
Phenylhydrazine hydrochloride is listed as being used in connection with the following API: Edaravone.
The listed synonym or IUPAC name for Phenylhydrazine hydrochloride is phenylhydrazine;hydrochloride.