Pemirolast potassium

Pemirolast Potassium is the potassium salt form of pemirolast, a pyrimidinone derivative with antiallergic property. Pemirolast potassium exerts its action by blocking the antigen-mediated calcium ion influx into mast cells. This prevents mast cell degranulation, resulting in mast cell stabilization and inhibition of the release of inflammatory mediators, histamine and leukotrienes, which are involved in the allergic process. Pemirolast potassium also prevents inflammatory mediator release from eosinophils. Its therapeutic use is listed as anti-asthmatic agents. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Pemirolast potassium salt, Pemilaston, Alamast and Alegysal. Its PubChem CID is 443866.