Pamapimod is a member of the class of pyridopyrimidines that is 8-methylpyrido[2,3-d]pyrimidin-7(8H)-one carrying additional (1,5-dihydroxypentan-3-yl)amino and 2,4-difluorophenoxy substituents at positions 2 and 6 respectively. It is a potent inhibitor of MAPK and is used for treatment of rheumatoid arthritis. The directory classifies it as a discontinued API with a synthetic source/manufacturing origin. Other names for this substance include Pyrido(2, 3-d)pyrimidin-7(8H)-one, 6-(2, 4-difluorophenoxy)-2-((3-hydroxy-1-(2-hydroxyethyl)propyl)amino)-8-methyl- and pamapimodum. Its PubChem CID is 16220188.
Pamapimod
| CAS No | 449811-01-2 |
|---|---|
| Molecular Formula | C19H20F2N4O4 |
| Molecular Weight | 406.4 g/mol |
| Synonyms | 6-(2,4-difluorophenoxy)-2-(1,5-dihydroxypentan-3-ylamino)-8-methylpyrido[2,3-d]pyrimidin-7-one |
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Frequently Asked Questions
Pamapimod is a member of the class of pyridopyrimidines that is 8-methylpyrido[2,3-d]pyrimidin-7(8H)-one carrying additional (1,5-dihydroxypentan-3-yl)amino and 2,4-difluorophenoxy substituents at positions 2 and 6 respectively.
The listed CAS number is 449811-01-2.
The listed molecular formula is C19H20F2N4O4.
The listed molecular weight is 406.4 g/mol.
6-(2,4-difluorophenoxy)-2-(1,5-dihydroxypentan-3-ylamino)-8-methylpyrido[2,3-d]pyrimidin-7-one.
The source lists Pyrido(2, 3-d)pyrimidin-7(8H)-one, 6-(2, 4-difluorophenoxy)-2-((3-hydroxy-1-(2-hydroxyethyl)propyl)amino)-8-methyl- and pamapimodum.