Palonosetron hydrochloride

Palonosetron hydrochloride is a selective 5-HT₃ receptor antagonist used to prevent chemotherapy-induced and postoperative nausea and vomiting. It has a long half-life and provides prolonged antiemetic protection. It is grouped under the following drug class(es): Antiemetics and Serotonin agents. Its therapeutic use is listed as gastrointestinal agents. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Aloxi, Onicit and posfrea. Its PubChem CID is 6918303.

CAS No 135729-62-3
Molecular Formula C19H25ClN2O
Molecular Weight 332.9 g/mol
Synonyms (3aS)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one;hydrochloride

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