Oxazolidin

Oxyphenbutazone is a metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome. Among its listed roles, it functions as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic, an antipyretic, a gout suppressant, a drug metabolite, a xenobiotic metabolite, an antineoplastic agent and an antimicrobial agent. It belongs to the class of pyrazolidines and a member of phenols. Functionally, it is related to phenylbutazone. Its therapeutic use is listed as anti-inflammatories. The directory classifies it as a unknown/inactive API with a synthetic source/manufacturing origin. Other names for this substance include Tandearil, Crovaril, Flogitolo, Flogoril, Visubutina and Oxyphenbutazone. Its PubChem CID is 4641.

CAS No 129-20-4
Molecular Formula C19H20N2O3
Molecular Weight 324.4 g/mol
Synonyms 4-butyl-1-(4-hydroxyphenyl)-2-phenylpyrazolidine-3,5-dione

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