Oxazepam

Oxazepam is an intermediate-acting, 3-hydroxybenzodiazepine used to treat alcohol withdrawal and anxiety disorders. Oxazepam, like related 3-hydroxybenzodiazepine [lorazepam], is considered less susceptible to pharmacokinetic variability based on patient-specific factors (e.g. age, liver disease) – this feature is advantageous as compared to other benzodiazepines, and is likely owing in part to oxazepam’s relatively simple metabolism. It is an active metabolite of both [diazepam] and [temazepam] and undergoes very little biotransformation following absorption, making it unlikely to participate in pharmacokinetic interactions. It is grouped under the following drug class(es): Anxiolytics, Benzodiazepines, Controlled drug substances, Neurotransmitter agents, Psychotropic agents, Schedule IV controlled substances and Sedatives. Its therapeutic use is listed as antianxiety drugs, central nervous system (CNS) agents and veterinary tranquilizers. The directory classifies it as a commercial API with a semi-synthetic source/manufacturing origin. Other names for this substance include Serax, Tazepam and Adumbran. It is listed as a controlled drug substance (Schedule IV). Its PubChem CID is 4616.

CAS No 604-75-1
Molecular Formula C15H11ClN2O2
Molecular Weight 286.71 g/mol
Synonyms 7-chloro-3-hydroxy-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one

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