Orlistat

Orlistat is a carboxylic ester resulting from the formal condensation of the carboxy group of N-formyl-L-leucine with the hydroxy group of (3S,4S)-3-hexyl-4-[(2S)-2-hydroxytridecyl]oxetan-2-one. A pancreatic lipase inhibitor, it is used as an anti-obesity drug. Among its listed roles, it functions as a EC 3.1.1.3 (triacylglycerol lipase) inhibitor, a bacterial metabolite, an EC 2.3.1.85 (fatty acid synthase) inhibitor and an anti-obesity agent. It is a beta-lactone, a L-leucine derivative, a member of formamides and a carboxylic ester. It is grouped under the following drug class(es): Pancreatic lipase inhibitors. Its therapeutic use is listed as anti-obesity agents and weight loss agents. The directory classifies it as a commercial API with a semi-synthetic source/manufacturing origin. Other names for this substance include Xenical, Alli, Orlipastat and tetrahydrolipastatin. Its PubChem CID is 3034010.

CAS No 96829-58-2
Molecular Formula C29H53NO5
Molecular Weight 495.7 g/mol
Synonyms [(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl] (2S)-2-formamido-4-methylpentanoate

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