Omacetaxine mepesuccinate is a cephalotaxine-derived alkaloid ester obtained from Cephalotaxus harringtonia; used for the treatment of chronic or accelerated phase chronic myeloid leukaemia. Among its listed roles, it functions as a antineoplastic agent, a protein synthesis inhibitor, an apoptosis inducer and an anticoronaviral agent. It is an alkaloid ester, a tertiary alcohol, an organic heteropentacyclic compound and an enol ether. Functionally, it is related to cephalotaxine. The directory classifies it as a discontinued API with a semi-synthetic source/manufacturing origin. Other names for this substance include Ceflatonin, Myelostat, Synribo and Omapro. Its PubChem CID is 285033.
Omacetaxine mepesuccinate
| CAS No | 26833-87-4 |
|---|---|
| Molecular Formula | C29H39NO9 |
| Molecular Weight | 545.6 g/mol |
| Synonyms | 1-O-[(2S,3S,6R)-4-methoxy-16,18-dioxa-10-azapentacyclo[11.7.0.02,6.06,10.015,19]icosa-1(20),4,13,15(19)-tetraen-3-yl] 4-O-methyl (2R)-2-hydroxy-2-(4-hydroxy-4-methylpentyl)butanedioate |
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Frequently Asked Questions
Omacetaxine mepesuccinate is a cephalotaxine-derived alkaloid ester obtained from Cephalotaxus harringtonia; used for the treatment of chronic or accelerated phase chronic myeloid leukaemia.
The listed CAS number is 26833-87-4.
The listed molecular formula is C29H39NO9.
The listed molecular weight is 545.6 g/mol.
1-O-[(2S,3S,6R)-4-methoxy-16,18-dioxa-10-azapentacyclo[11.7.0.02,6.06,10.015,19]icosa-1(20),4,13,15(19)-tetraen-3-yl] 4-O-methyl (2R)-2-hydroxy-2-(4-hydroxy-4-methylpentyl)butanedioate.
The source lists Ceflatonin, Myelostat, Synribo and Omapro.