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Estropipate is a natural estrogenic substance composed of estrone sulfate and piperazine. Estropipate diffuses through the cell membrane and binds to and subsequently activates the nuclear estrogen receptor found in the reproductive tract, breast, pituitary, hypothalamus, liver, and bone. The activated complex binds to the estrogen response element on the DNA and activates the transcription of genes involved in the functioning of the female reproductive system and secondary sex characteristics. It is grouped under the following drug class(es): Estrogens. The directory classifies it as a discontinued API with a natural source/manufacturing origin. Other names for this substance include Piperazine estrone sulfate, 7280-37-7, Sulestrex and Estropipate. Its PubChem CID is 5284555.

CAS No 7280-37-7
Molecular Formula C22H32N2O5S
Molecular Weight 436.6 g/mol
Synonyms [(8R,9S,13S,14S)-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl] hydrogen sulfate;piperazine

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