Obeticholic acid is a dihydroxy-5beta-cholanic acid that is chenodeoxycholic acid carrying an additional ethyl substituent at the 6alpha-position. A semi-synthetic bile acid which functions as a farnesoid X receptor agonist and is used for treatment of primary biliary cholangitis. Among its listed roles, it functions as a farnesoid X receptor agonist and a hepatoprotective agent. It is a dihydroxy-5beta-cholanic acid, a 3alpha-hydroxy steroid and a 7alpha-hydroxy steroid. Functionally, it is related to chenodeoxycholic acid. The directory classifies it as a commercial API with a semi-synthetic source/manufacturing origin. Other names for this substance include 6-ECDCA, Ocaliva, 6-Ethylchenodeoxycholic acid, 6-ethyl-3 and 7-dihydroxycholan-24-oic acid. Its PubChem CID is 447715.
Obeticholic acid
| CAS No | 459789-99-2 |
|---|---|
| Molecular Formula | C26H44O4 |
| Molecular Weight | 420.6 g/mol |
| Synonyms | (4R)-4-[(3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid |
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Frequently Asked Questions
Obeticholic acid is a dihydroxy-5beta-cholanic acid that is chenodeoxycholic acid carrying an additional ethyl substituent at the 6alpha-position. A semi-synthetic bile acid which functions as a farnesoid X receptor agonist and is used for treatment of primary biliary cholangitis.
The listed CAS number is 459789-99-2.
The listed molecular formula is C26H44O4.
The listed molecular weight is 420.6 g/mol.
(4R)-4-[(3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid.
The source lists 6-ECDCA, Ocaliva, 6-Ethylchenodeoxycholic acid, 6-ethyl-3 and 7-dihydroxycholan-24-oic acid.