Nicotine

(S)-nicotine is a 3-(1-methylpyrrolidin-2-yl)pyridine in which the chiral centre has S-configuration. The naturally occurring and most active enantiomer of nicotine, isolated from Nicotiana tabacum. Among its listed roles, it functions as a phytogenic insecticide, a teratogenic agent, a neurotoxin, an anxiolytic drug, a nicotinic acetylcholine receptor agonist, a biomarker, an immunomodulator, a mitogen, a peripheral nervous system drug, a psychotropic drug, a plant metabolite and a xenobiotic. It is the conjugate base of (S)-nicotinium(1+). It is an enantiomer of a (R)-nicotine. It is grouped under the following drug class(es): Neurotransmitter agents. Its therapeutic use is listed as smoking cessation agents. The directory classifies it as a commercial API with a natural source/manufacturing origin. Other names for this substance include L-Nicotine, Habitrol, Nicotrol, Prostep and Tendust. Its PubChem CID is 89594.