Naltrexone

Naltrexone is an organic heteropentacyclic compound that is naloxone substituted in which the allyl group attached to the nitrogen is replaced by a cyclopropylmethyl group. A mu-opioid receptor antagonist, it is used to treat alcohol dependence. Among its listed roles, it functions as a mu-opioid receptor antagonist, a central nervous system depressant, an environmental contaminant, a xenobiotic and an antidote to opioid poisoning. It is an organic heteropentacyclic compound, a morphinane-like compound and a member of cyclopropanes. It is the conjugate base of naltrexone(1+). It is grouped under the following drug class(es): Opioid dependence agents. Its therapeutic use is listed as alcohol dependence agents and weight loss agents. The directory classifies it as a commercial API with a semi-synthetic source/manufacturing origin. Other names for this substance include Vivitrol, Vivitrex and Celupan. Its PubChem CID is 5360515.

CAS No 16590-41-3
Molecular Formula C20H23NO4
Molecular Weight 341.4 g/mol
Synonyms (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one

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