Nafcillin sodium

Nafcillin Sodium Anhydrous is the anhydrous form of the sodium salt of nafcillin, a narrow-spectrum beta-lactamase-resistant penicillin with antibacterial activity. Nafcillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis. It is grouped under the following drug class(es): Beta-lactams and Penicillins. Its therapeutic use is listed as anti-infectives and antibacterials. The directory classifies it as a commercial API with a semi-synthetic source/manufacturing origin. Other names for this substance include Sodium nafcillin, Nafcillin sodium anhydrous and Nallpen. Its PubChem CID is 23667630.

CAS No 985-16-0
Molecular Formula C21H21N2NaO5S
Molecular Weight 436.5 g/mol
Synonyms sodium;(2S,5R,6R)-6-[(2-ethoxynaphthalene-1-carbonyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

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