It serves as an alkylating agent, typically reacting with 2-guanidino-4-mercaptomethyl-thiazole to introduce the necessary sulfamyl-propionamidine side chain with high yields, often exceeding 70%. N-Sulfamyl-3-chloropropionamidine hydrochloride is a critical intermediate employed to synthesize the anti-ulcer drug Famotidine.
N-Sulphamyl-3-chloropropionamidine hydrochloride
| API Name | Famotidine |
|---|---|
| CAS No | 106649-95-0 |
| Molecular Formula | C3H9Cl2N3O2S |
| Molecular Weight | 222.09 g/mol |
| Synonyms | 3-chloro-N'-sulfamoylpropanimidamide;hydrochloride |
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