N-Acetyl calicheamicin is used as a potent cytotoxic agent in antibody-drug conjugates (ADCs) for cancer therapy. The directory classifies it as a commercial API with a semi-synthetic source/manufacturing origin. Other names for this substance include N-Acetylcalicheamicin Gamma and N-Acetyl-Gamma-Calicheamicin. It is also listed for alternate use as: API Intermediate. Its PubChem CID is 134819845.
N-Acetyl calicheamicin
| CAS No | 108212-76-6 |
|---|---|
| Molecular Formula | C57H76IN3O22S4 |
| Molecular Weight | 1410.4 g/mol |
| Synonyms | S-[(2R,3S,4S,6S)-6-[[(2R,3S,4S,5R,6R)-5-[(2S,4S,5S)-5-[acetyl(ethyl)amino]-4-methoxyoxan-2-yl]oxy-4-hydroxy-6-[[(2S,5Z,9R)-9-hydroxy-12-(methoxycarbonylamino)-13-[2-(methyltrisulfanyl)ethylidene]-11-oxo-2-bicyclo[7.3.1]trideca-1(12),5-dien-3,7-diynyl]oxy]-2-methyloxan-3-yl]amino]oxy-4-hydroxy-2-methyloxan-3-yl] 4-[(2S,3R,4R,5S,6S)-3,5-dihydroxy-4-methoxy-6-methyloxan-2-yl]oxy-5-iodo-2,3-dimethoxy-6-methylbenzenecarbothioate |
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Frequently Asked Questions
N-Acetyl calicheamicin is used as a potent cytotoxic agent in antibody-drug conjugates (ADCs) for cancer therapy. The directory classifies it as a commercial API with a semi-synthetic source/manufacturing origin.
The listed CAS number is 108212-76-6.
The listed molecular formula is C57H76IN3O22S4.
The listed molecular weight is 1410.4 g/mol.
The source lists N-Acetylcalicheamicin Gamma and N-Acetyl-Gamma-Calicheamicin.
It is listed as a commercial API with a semi-synthetic origin.